TY - JOUR AU - Maria Gabriella Malzone AU - Marzio Di Meglio AU - Dario Furgiuele AU - Nicola Galantuomo AU - Sabrina Alfano AU - Gennaro Mossetti PY - 2021/06/30 Y2 - 2024/03/28 TI - Primary non-Hodgkin diffuse large B-cell lymphoma of the lacrimal sac: a rare case of aggressive tumor and literature review JF - Medicine and Pharmacy Reports JA - Medicine and Pharmacy Reports VL - 94 IS - 3 SE - Case Report DO - 10.15386/mpr-1926 UR - https://medpharmareports.com/index.php/mpr/article/view/1926 AB - Primary malignant lymphomas of the lacrimal sac are rare neoplasms. They are mainly B-cell lymphoma with nonspecific and atypical symptoms, which can lead to misdiagnosis and a delay in the appropriate cure. Early diagnosis made by biopsy and the right choice of treatments can increase the chance of survival. We report a case of a non-Hodgkin diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac, involving also the drainage system, in a 77-year-old female. She presented with an epiphora, swelling and a heavy visual impairment at the left eye successfully treated with cycles of polychemotherapy and radiotherapy. ER -