Encapsulated papillary variant of medullary carcinoma of thyroid with extensive cystic change: an extremely rare presentation

Authors

  • Monika Singh Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, Delhi, India (PGIMER), Dr RML Hospital New Delhi, India
  • Arvind Ahuja Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences, Dr RML Hospital New Delhi, India
  • Seema Rahar Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, Delhi, India (PGIMER), Dr RML Hospital New Delhi, India
  • Minakshi Bhardwaj Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences, New Delhi, Delhi, India (PGIMER), Dr RML Hospital New Delhi, India

DOI:

https://doi.org/10.15386/mpr-1570

Keywords:

medullary carcinoma papillary variant, cystic change, thyroid, immunohistochemistry

Abstract

Papillary variant of medullary carcinoma of the thyroid is an unusual subtype with many diagnostic challenges. The  authors report a case of papillary variant of thyroid medullary carcinoma in a 37- year-old female, who presented with complaints of pain in the thyroid nodule  for the latter  two months. Contrast enhanced computed tomography (CECT) neck revealed an enlarged and heterogeneously enhancing left lobe of thyroid. This was followed by hemithyroidectomy for suspicion of colloid goitre. Gross examination of the cut surface of the thyroid parenchyma had a sponge like appearance. On histopathology a diagnosis of encapsulated papillary variant of medullary carcinoma thyroid was made with the help of special stains and immunohistochemistry (IHC).

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Published

2020-09-08

How to Cite

1.
Singh M, Ahuja A, Rahar S, Bhardwaj M. Encapsulated papillary variant of medullary carcinoma of thyroid with extensive cystic change: an extremely rare presentation. Medicine and Pharmacy Reports [Internet]. 2020 Sep. 8 [cited 2025 Jun. 20];94(3):372-6. Available from: https://medpharmareports.com/index.php/mpr/article/view/1570

Issue

Vol. 94 No. 3 (2021)

Section

Case Report

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