Successful desensitization in a patient with hypersensitivity to multiple Insulin preparations - case report

Authors

  • Carina Petricău
  • Irena Nedelea
  • Diana Deleanu

DOI:

https://doi.org/10.15386/mpr-1643

Keywords:

insulin, drug allergy, hypersensitivity, immunotherapy

Abstract

Hypersensitivity to insulin has decreased substantially in the past three decades, since purified human insulin was introduced to replace heterogeneous porcine and bovine preparations. However, human insulin and its analogs still have immunogenic potential that may prove detrimental for hypersensitive insulin-dependent diabetics. In cases of anaphylactic reactions to insulin, rapid desensitization may be considered as a treatment strategy. We present the first case of successful insulin desensitization in Romania for an uncontrolled diabetic patient with type I hypersensitivity to multiple insulin analogs.

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Published

2020-11-27

How to Cite

1.
Petricău C, Nedelea I, Deleanu D. Successful desensitization in a patient with hypersensitivity to multiple Insulin preparations - case report. Med Pharm Rep [Internet]. 2020 Nov. 27 [cited 2025 Oct. 2];94(2):248-51. Available from: https://medpharmareports.com/index.php/mpr/article/view/1643

Issue

Section

Case Report