Introduction to the Human Endocannabinoid System: Cannabinoid Receptors and Endogenous Ligands

Authors

  • Stanislav Grosu

Keywords:

cannabinoid receptors, endocannabinoids, physiology

Abstract

The endocannabinoid system in humans is responsible for the majority of physiological protection processes. The cannabinoid receptors CB1 and CB2 modulate the activity of endocannabinoids, such as anandamide, 2-arachydonoylglycerol, virodhamine and others. Some of the most important functions of the cannabinoid receptors and endogenous ligands are neuronal plasticity and nerve regeneration, nociception and pain modulation, cognitive, mnestic and psychoemotional profile correction, also inflamatory, immune, metabolic and alimentary control, sleep and motricity improvement, as well as inhibitory effects in cancer.

Author Biography

Stanislav Grosu, Spitalul Clinic de Psihiatrie, Chişinău, USMF “Nicolae Testemiţanu”, Chişinău

Catedra Psihiatrie, Narcologie Si Psihologie Medicală,

Disciplina Fiziologia Omului, Catedra Fiziologia Omului și Biofizică

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Published

2014-02-15

How to Cite

1.
Grosu S. Introduction to the Human Endocannabinoid System: Cannabinoid Receptors and Endogenous Ligands. Med Pharm Rep [Internet]. 2014 Feb. 15 [cited 2025 Oct. 6];85(3):298-301. Available from: https://medpharmareports.com/index.php/mpr/article/view/165

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Section

Reviews