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© Medicine and Pharmacy Reports, 2022
Affiliations
Tiberiu Rareș Moldovan
Medical Oncology, "Prof. Dr. Ion Chiricuta" Oncology Institue, Cluj-Napoca, Romania
Călin Căinap
“Prof. Dr. Ion Chiricuță” Oncology Institute, Cluj-Napoca, Romania; Oncology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Zsolt Fekete
Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Emil Pușcaș
“Prof. Dr. Ion Chiricuță” Oncology Institute, Cluj-Napoca, Romania; Oncology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Andrei Roman
“Prof. Dr. Ion Chiricuță” Oncology Institute, Cluj-Napoca, Romania; Medical Radiology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Rareș Buiga
“Prof. Dr. Ion Chiricuță” Oncology Institute, Cluj-Napoca, Romania; Pathology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Diana Olteanu
“Prof. Dr. Ion Chiricuță” Oncology Institute, Cluj-Napoca, Romania
Mădălina Bota
Mother and Child Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Simona Căinap
Mother and Child Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Ovidiu Bochiș
“Prof. Dr. Ion Chiricuță” Oncology Institute, Cluj-Napoca, Romania
How to Cite
Signet ring cell gastric carcinoma with breast and leptomeningeal metastases: a case report
Abstract
Gastric cancer is the 5th most common malignancy worldwide. Signet ring cell histology represents an aggressive subtype of gastric cancer, presenting at a younger age. Both breast and leptomeningeal metastases are rare locations of tumor dissemination, requiring correct and immediate diagnosis and treatment. We present a case of a 45-year old female with signet ring cell gastric carcinoma who developed both left breast and leptomeningeal metastases, requiring multiple chemotherapy lines. As far as we know, this is the first published case in literature following multiple lines of treatment for both breast and leptomeningeal metastases from signet ring cell gastric carcinoma.