Comparative evaluation of the efficacy of the desensitizing and remineralizing agent in the reduction of dentin hypersensitivity after orthodontic debonding - a randomised clinical trial
Introduction. Enamel loss is a common problem during various orthodontic procedures. The study aims to compare the efficacy of a desensitizer and remineraliszer in the reduction of the dentin hypersensitivity ( DH) associated with enamel microcracks after orthodontic debonding.
Methods. A unicentric two arm parallel study with 30 subjects randomly assigned to each groups following debonding. Group-1 subjects were treated with Gluma® desensitizer(5% glutaraldehyde and 35% hydroxyethyl methacrylate (HEMA)) and the Group-2 intervention included a remineralizing agent GC Tooth Mousse Plus® ( casein phospho peptide and amorphous calcium Fluro phosphate ( (CPP:ACFP). The Visual Analogue Scale (VAS) was utilized to evaluated DHas subjective perception of pain following the Air blast test and cold test. The VAS scale was indexed from 0-10 markings based on the intensity of perception. Five different time points T0 and T1-immediately after debonding and intervention on day 1, T2- 48 hours, and T3 after 72 hours were taken for the assessment of VAS scores.
Results. The VAS scores for the airblast test for group 1 were (2.73,0, 0.06, 0.03) and group 2 (2.46,0,0.16.0.13) at different periods. The sensitivity scores for the cold blast test for group 1 were (2.73,0, 0.13, 0.03) and for group 2 (2.46,0, 0.16, 0.13). There was 98 percent reduction in DH between T0 and T3 and was statistically significant( p<0.05) for both the groups.
Conclusion. Gluma® desensitizer and GC Tooth Mousse Plus® are equally effective in the reduction of DH in the orthodontic patient following debonding.