Correlation between the prevalence of T-cell lymphomas and alcohol consumption

Authors

  • Minodra Desmirean
  • Cedric Richlitzki
  • Sergiu Pasca
  • Patric Teodorescu
  • Bobe Petrushev
  • Sebastian Rauch
  • Jakob Steinheber
  • Sabina Iluta
  • Jiaxin Liu
  • Delia Dima
  • Ravnit Grewal
  • Weina Ma
  • Liren Qian
  • Ciprian Tomuleasa

DOI:

https://doi.org/10.15386/mpr-1777

Keywords:

T-cell lymphomas, alcohol consumption, pathophysiology

Abstract

Background and aims. Alcohol is a psychoactive substance that causes dependence, with many thousands of years in the history of mankind, being widely used in different cultures. According to the International Agency for Research on Cancer, alcohol is involved in the development of cancer, being directly associated with it. Considering that alcohol is involved in the initiation and dissemination of gastrointestinal malignancies, the objective of the study was to assess its role in the pathogenesis of T-cell lymphomas, as well as its possible correlation with chronic consumption.

Methods. The patient cohort was compiled from the Sixth Medical Center of the People’s Liberation Army Navy General Hospital in Beijing, China. A total of 30 patients matched the criteria and were enrolled in the study. Statistical analysis of the raw data was performed using R Statistics version R 3.5.1. released on the 29.08.2018.

Results. Our data demonstrate that the most common extranodal involvment of T-cell lymphoma patients is represented in decreasing order by bone marrow, peritoneum, rhino-oropharynx and the liver-biliary system. Nodal involvement is mainly represented in decreasing order by the laterocervical, axillary, mediastinal and inguinal regions.

Conclusions. These findings may be of value in further research and practical/clinical settings. Fever is the most common clinical feature and was present in most studied patients.

Downloads

Published

2021-06-30

How to Cite

1.
Desmirean M, Richlitzki C, Pasca S, Teodorescu P, Petrushev B, Rauch S, Steinheber J, Iluta S, Liu J, Dima D, Grewal R, Ma W, Qian L, Tomuleasa C. Correlation between the prevalence of T-cell lymphomas and alcohol consumption. Med Pharm Rep [Internet]. 2021 Jun. 30 [cited 2025 Oct. 28];94(3):298-306. Available from: https://medpharmareports.com/index.php/mpr/article/view/1777

Issue

Vol. 94 No. 3 (2021)

Section

Original Research

License

The authors are required to transfer the copyright of the published paper to the journal. This is done by agreeing to sign the Copyright Assignment Form. Whenever the case, authors are also required to send permissions to reproduce material (such as illustrations) from the copyright holder.

 Creative Commons License
The papers published in the journal are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.