Impact of high-intensity interval training on cardio-metabolic health outcomes and mitochondrial function in older adults: a review

Authors

  • Simran Mahatme Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India, 576104
  • Vaishali K Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India, 576104 https://orcid.org/0000-0001-5746-1682
  • Nitesh Kumar Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India
  • Vanishree Rao Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of higher Education, Manipal, Karnataka, India
  • Rakesh Krishna Kovela Department of Neurophysiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, Maharashtra India. 442001
  • Mukesh Kumar Sinha Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India, 576104

DOI:

https://doi.org/10.15386/mpr-2201

Keywords:

high-intensity exercise, healthy aging, quality of life, cardiorespiratory fitness

Abstract

Exercise being a potent stimulator of mitochondrial biogenesis, there is a need to investigate the effects of high-intensity interval training (HIIT) among older adults. This review explores and summarizes the impact of HIIT on mitochondria and various cardio-metabolic health outcomes among older adults, healthy and with comorbid conditions. Electronic databases were scrutinized for literature using permutations of keywords related to (i) Elderly population (ii) HIIT (iii) Mitochondria, cell organelles, and (iv) cardio-metabolic health outcomes. Twenty-one studies that met the inclusion criteria are included in this review. HIIT is an innovative therapeutic modality in preserving mitochondrial quality with age and serves to be a viable, safe, and beneficial exercise alternative in both ill and healthy older adults.

 

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Published

2022-04-20

How to Cite

1.
Mahatme S, K V, Kumar N, Rao V, Kovela RK, Sinha MK. Impact of high-intensity interval training on cardio-metabolic health outcomes and mitochondrial function in older adults: a review. Medicine and Pharmacy Reports [Internet]. 2022 Apr. 20 [cited 2025 Jun. 20];95(2):115-30. Available from: https://medpharmareports.com/index.php/mpr/article/view/2201

Issue

Vol. 95 No. 2 (2022)

Section

Reviews

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