Digestive involvement in the Long-COVID syndrome

Authors

  • Alina M. Bogariu
  • Dan L. Dumitrascu

DOI:

https://doi.org/10.15386/mpr-2340

Keywords:

COVID-19, digestive diseases, SARS-Cov-2 infection, gastrointestinal tract, liver diseases, long-Covid, sequelae

Abstract

Background and aim. The SARS-CoV-2 infection which caused a worldwide epidemic was considered first a lung disease. Later on, it was found that the disease caused by this virus, SARS-CoV-2, can affect most organs, including the digestive system. The long-term effects of this infection are now progressively detected and called Long-COVID. This review aims is to present the updated knowledge of the digestive sequelae after SARS-CoV-2 infection.

Methods. A search was performed in the main medical literature databases. The following search terms were used: long-covid, gastrointestinal or gastric sequelae SARS-CoV-2 and COVID-19. Data on gastrointestinal symptoms after 12 weeks were collected and presented. Observational studies were included. Studies that focus only on acute COVID-19 infection (<4 weeks) were excluded.

Results. The main symptoms that can occur in the long term are: diarrhea, nausea, vomiting, abdominal pain, along with increased liver enzymes. Patients with chronic diseases have a higher risk of developing long-term sequelae, but it is not documented that digestive sequelae are influenced by the presence of chronic diseases.

Conclusions. The SARS-CoV-2 virus can affect any part of the digestive system not only in the acute infection phase but also for longer time, leaving long-term sequelae.

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Published

2021-12-21

How to Cite

1.
Bogariu AM, Dumitrascu DL. Digestive involvement in the Long-COVID syndrome. Med Pharm Rep [Internet]. 2021 Dec. 21 [cited 2025 Oct. 5];95(1):5-10. Available from: https://medpharmareports.com/index.php/mpr/article/view/2340

Issue

Section

Reviews