Acute onset of Lambert Eaton myasthenic syndrome in prostate adenocarcinoma: a case report
DOI:
https://doi.org/10.15386/mpr-2541Keywords:
Lambert Eaton myasthenic syndrome, voltage-gated calcium channels, neurophysiologyAbstract
Lambert Eaton myasthenic syndrome (LEMS) is a rare disorder of the neuromuscular junction. The representative clinical triad consists of proximal muscular weakness, areflexia and autonomic dysfunction. The diagnosis is based on the clinical findings confirmed by voltage-gated calcium channels antibody titer and neurophysiology. We present a 69 year old male with prostate adenocarcinoma and 30 years history of smoking, referred for muscle weakness in the lower limbs and difficulty to climb the stairs.
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