Long-term results of multimodal treatment of the prostate using the Thulium Laser

Authors

  • Roxana Andra Coman Department of Urology, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania, Endoplus Clinic, Cluj-Napoca, Romania
  • Daniel Corneliu Leucuta Department of Medical Informatics and Biostatistics, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.
  • Radu Tudor Coman Department of Epidemiology, Iuliu Hatieganu University of Medicine and Pharmacy, 400347 Cluj-Napoca, Romania
  • Carmen Lapusan Endoplus Clinic, Cluj-Napoca, Romania
  • Dan Vasile Stanca Department of Urology, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania Endoplus Clinic, Cluj-Napoca, Romania
  • Ioan Coman Department of Urology, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania, Endoplus Clinic, Cluj-Napoca, Romania
  • Nadim Al Hajjar Department of Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Surgery, “Octavian Fodor” Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania

DOI:

https://doi.org/10.15386/mpr-2760

Keywords:

benign prostatic hyperplasia, non-anatomic technique, long-term results, thulium laser

Abstract

Background and aims. To evaluate a novel multimodal treatment (TLP) that integrates the use of a thulium laser, bipolar transurethral resection of the prostate (TURP), and “button-type” bipolar plasma vaporization for the endoscopic treatment of benign prostatic hyperplasia (BPH).

Methods. From March 2018 to December 2021, we prospectively evaluated 220 patients with symptomatic BPH who underwent TLP. Patients were assessed based on the International Prostate Symptom Score (IPSS), quality of life (QoL), maximum urinary flow rate (Qmax), and postvoid residual urine (PVR). Perioperative and postoperative follow-up data were analyzed.

Results. The mean age at surgery was 66.74 years (SD 8.21). The median prostate size was 80 (IQR 70 - 110). The median operative time was 45 (IQR 35 - 55) minutes and the hospital stay was 2 (IQR 1 - 2) days. Patients were discharged with the urinary catheter in place, which was removed approximately 7 days after surgery when the histopathological result was discussed with the patient. Postoperatively, IPSS, QoL, Qmax and PVR showed a significant improvement starting at 3 months and continued through the postoperative follow-up visits (6- 12-24-36-48-60 months). Urethral stricture and bladder neck contracture occurred in 1 (0.45%) and 2 (0.91%) patients, respectively. Recurrence of BPH occurred in 2 patients (0.91%) who underwent a second procedure.

Conclusions. In conclusion, we report that the multimodal surgical treatment of BPH consisting of combining Thulium laser vaporization, bipolar TURP and plasma vaporization (TLP) represents an efficient and durable therapeutic method for BPH patients with low a complication rate at 5-year follow-up.

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Published

2024-07-05

How to Cite

1.
Coman RA, Leucuta DC, Coman RT, Lapusan C, Stanca DV, Coman I, Al Hajjar N. Long-term results of multimodal treatment of the prostate using the Thulium Laser. Medicine and Pharmacy Reports [Internet]. 2024 Jul. 5 [cited 2025 Jun. 20];97(3):338-46. Available from: https://medpharmareports.com/index.php/mpr/article/view/2760

Issue

Vol. 97 No. 3 (2024)

Section

Original Research

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