Is colorectal cancer associated with diabetes mellitus ?

Authors

  • Cătălina Zaharia
  • Aurel Mironiuc
  • Raluca Pais
  • Dan L. Dumitraşcu

Keywords:

colorectal cancer, diabetes mellitus, gastric cancer, metabolic syndrome

Abstract

Background and aim. There is increasing evidence on the association of the metabolic syndrome with the colorectal cancer. We looked for the association of diabetes mellitus, a main component of the metabolic syndrome, with colorectal cancer.
Methods. We looked for all new cases of colorectal cancer in two tertiary centers of a single research center (one of internal medicine with profile of gastroenterology and one of general surgery) in an interval of three years. This was a retrospective study of a series of cases. The cases of gastric cancer collected from the same records served as controls. Comparison between diabetic and non-diabetic patients was performed.
Results. A number of 114 cases with colorectal cancer and of 31 gastric cancer were obtained for analysis. Our data suggest that the colorectal cancer is associated with diabetes in obese patients. On the other hand, the females with diabetes have a double risk of gastric cancer compared to females without diabetes.
Conclusion. Although the association between colorectal cancer and diabetes remains debated, it seems that obesity associated with diabetes is a predisposing factor for colorectal cancer. The risk of gastric cancer in diabetic females deserves further investigation.

Author Biography

Aurel Mironiuc, Center for the Research of Chronic Diseases

 2nd Dept. of Internal Medicine and 2nd Dept. of Surgery

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Published

2012-01-30

How to Cite

1.
Zaharia C, Mironiuc A, Pais R, Dumitraşcu DL. Is colorectal cancer associated with diabetes mellitus ?. Med Pharm Rep [Internet]. 2012 Jan. 30 [cited 2025 Oct. 5];85(1):59-61. Available from: https://medpharmareports.com/index.php/mpr/article/view/322

Issue

Vol. 85 No. 1 (2012)

Section

Original Research

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