METHODS OF ASSESSING LIVER MORPHOLOGY

Authors

  • Teodora Alexescu
  • Vasile Negrean
  • Nicolae Rednic
  • Olga Orăşan
  • Monica Lencu
  • Simina Ţărmure

Keywords:

chronic liver disease, liver biopsy, noninvasive methods for hepatic assessment

Abstract

Due to the increasing incidence and prevalence of patients with chronic liver diseases, especially hepatitis B and / or hepatitis C virus infection, we need advanced medical instruments for measuring liver fibrosis and prognosis estimation, necessary to establish standardized indications for antiviral therapy and to monitor the response to therapy.

We will review the methods for assessing liver morphology: invasive methods (liver biopsy, currently considered the “gold standard” in the diagnosing and staging of chronic liver disease) and new noninvasive methods for assessment of the liver, such as: serum biomarkers, elastography, Fibrotest, Fibromax, Hepascore, APRI (AST / pallets ratio index), ASPRI (age-spleen-platelet index), ELF (the European Liver fibrosis panel), ARFI (Acoustic Radiation Force Impulse Imaging), S-index.

Author Biographies

Teodora Alexescu, UMF „Iuliu Haţieganu” Cluj-Napoca

Clinica Medicală IV

Vasile Negrean, UMF „Iuliu Haţieganu” Cluj-Napoca

Clinica Medicală IV

Nicolae Rednic, Spitalul Clinic CF Cluj-Napoca

Spitalul Clinic CF Cluj-Napoca

Olga Orăşan, UMF „Iuliu Haţieganu” Cluj-Napoca

Clinica Medicală IV

Monica Lencu, Spitalul Clinic CF Cluj-Napoca

Spitalul Clinic CF Cluj-Napoca

Simina Ţărmure, UMF „Iuliu Haţieganu” Cluj-Napoca

Clinica Medicală IV

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Published

2011-11-17

How to Cite

1.
Alexescu T, Negrean V, Rednic N, Orăşan O, Lencu M, Ţărmure S. METHODS OF ASSESSING LIVER MORPHOLOGY. Med Pharm Rep [Internet]. 2011 Nov. 17 [cited 2025 Oct. 6];84(4):481-5. Available from: https://medpharmareports.com/index.php/mpr/article/view/342

Issue

Vol. 84 No. 4 (2011)

Section

Reviews

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