The role of dental stem cells in regeneration

Authors

  • Monica Angela Maxim
  • Olga Soritau
  • Mihaela Baciut
  • Simion Bran
  • Grigore Baciut

DOI:

https://doi.org/10.15386/cjmed-475

Keywords:

Dental stem cells, tissue regeneration, characterization, mesenchymal stem cells, tissue engineering

Abstract

Mesenchymal stem cells (MSCs) are adult stem cells that have the capacity of rising multiple cell types.

A rich source of mesenchymal stem cells is represented by the dental tissues: the periodontal ligament, the dental pulp, the apical papilla, the dental follicle and the deciduous teeth.

The aim of this review is to characterize the main dental- derived mesenchymal stem cell population, and to show their important role in tissue regeneration based on their properties : the multi-potency, the high proliferation rate, the differentiation in multiple cell lineages, the high cell viability and the positive expression for mesenchymal cell markers.

Tissue regeneration or de novo' formation of craniofacial structures is the future of regenerative medicine, offering a solution for congenital malformations, traumas and other diseases.

 

Author Biographies

Monica Angela Maxim, Universitatea de Medicina si Farmacie ''Iuliu Hatieganu'' Cluj-Napoca

Department

Olga Soritau, Institutul Oncologic ''Prof.Dr.Ion Chiricuta''

Department

Mihaela Baciut, Universitatea de Medicina si Farmacie "Iuliu Hatieganu'' Cluj- Napoca

Profesor universitar: Catedra de Chirurgie Cranio-Maxilofaciala si Urgente in Medicina Dentara, Universitatea de Medicina si Farmacie ’’Iuliu Hatieganu’’ Cluj-Napoca, Facultatea de Medicina Dentara

Simion Bran, Universitatea de Medicina si Farmacie "Iuliu Hatieganu'' Cluj- Napoca

Conferentiar universitar: Catedra de Chirurgie Cranio-Maxilofaciala si Urgente in Medicina Dentara, Universitatea de Medicina si Farmacie ’’Iuliu Hatieganu’’ Cluj-Napoca, Facultatea de Medicina Dentara

Grigore Baciut, Universitatea de Medicina si Farmacie "Iuliu Hatieganu'' Cluj- Napoca

Profesor universitar: Catedra de Chirurgie Cranio-Maxilofaciala si Urgente in Medicina Dentara, Universitatea de Medicina si Farmacie ’’Iuliu Hatieganu’’ Cluj-Napoca, Facultatea de Medicina Dentara

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Published

2015-09-20

How to Cite

1.
Maxim MA, Soritau O, Baciut M, Bran S, Baciut G. The role of dental stem cells in regeneration. Med Pharm Rep [Internet]. 2015 Sep. 20 [cited 2025 Oct. 3];88(4):479-82. Available from: https://medpharmareports.com/index.php/mpr/article/view/475

Issue

Vol. 88 No. 4 (2015)

Section

Reviews

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