The role of hormones in the pathogenesis of psoriasis vulgaris

Authors

  • Iulia Ioana Roman
  • Anne-Marie Constantin
  • Mihaela Elena Marina
  • Remus Ioan Orasan

DOI:

https://doi.org/10.15386/cjmed-505

Keywords:

psoriasis vulgaris, sex hormones, prolactin, glucocorticoids

Abstract

Psoriasis vulgaris is a chronic, common skin disease, which affects the patient’s quality of life to the highest degree. Several exogenous factors and endogenous hormonal changes may act as triggers for psoriasis.

The skin possesses a true endocrine system, which is very important in multiple systemic diseases. A number of conditions are associated with psoriasis, and its severity can also be influenced by hormones. Even though the sex hormones and prolactin have a major role in psoriasis pathogenicity, there are a lot of other hormones which can influence the psoriasis clinical manifestations: glucocorticoids, epinephrine, thyroid hormones, and insulin.

Author Biographies

Iulia Ioana Roman, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca

Physiology Discipline, Functional Sciences Department 2

Anne-Marie Constantin, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca

Histology Discipline, Morphological Sciences Department 1

Mihaela Elena Marina, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca

Histology Discipline, Morphological Sciences Department 1

Remus Ioan Orasan, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca

Physiology Discipline, Functional Sciences Department 2

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Published

2015-09-20

How to Cite

1.
Roman II, Constantin A-M, Marina ME, Orasan RI. The role of hormones in the pathogenesis of psoriasis vulgaris. Med Pharm Rep [Internet]. 2015 Sep. 20 [cited 2025 Oct. 26];89(1):11-8. Available from: https://medpharmareports.com/index.php/mpr/article/view/505

Issue

Vol. 89 No. 1 (2016)

Section

Reviews

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