A case control study of risk factors associated with pulmonary tuberculosis in Romania: Experience at a clinical hospital of pneumology

Authors

  • Pacifique Ndishimye
  • Bianca Domokos
  • Jonathan Stillo
  • Fouad Seghrouchni
  • Oulaya Mrabet
  • Daniela Homorodean
  • Carmen Monica Pop
  • Abderrahim Sadak

DOI:

https://doi.org/10.15386/cjmed-652

Keywords:

Tuberculosis, Risk factors, Prevention, Odds ratio, Romania.

Abstract


Background and aim. Tuberculosis (TB) remains a major public health issue in Romania. The aim of the present study was to evaluate the potential demographic, socioeconomic and behavioral risk factors for TB among hospitalized patients in Romania.

Methods. This is a case-control study conducted between March 1st 2014 and March 30th 2015 at Leon Daniello Clinical Hospital of Pneumology, Cluj Napoca. A total of 150 TB patients defined as “cases” were matched for age, sex and county of residence to 150 controls selected from patients attending the same hospital with respiratory diseases other than TB. Data collection was obtained through patient interviews using a structured questionnaire. Factors potentially associated with TB infection were analyzed using univariate and multivariate logistic regression.

Results. Factors independently associated with TB were illiteracy (OR=2.42, 95% CI 1.09-5.37), unemployment (OR=2.08, 95% CI 1.23-3.53), low household income (OR=4.12, 95% CI 2.53-6.71), smoking (more than 20 cigarettes per day) (OR=2.12, 95% CI 1.20-3.74), poor knowledge of TB (OR=3.46, 95% CI 1.97-6.07), presence of TB patient in household (OR=4.35, 95% CI 1.42-13.36), prior TB treatment (OR=2.2, 95% CI 1.93-2.5) and diabetes (OR=3.32, 95% CI 1.36-8.08).

Conclusion. This study provided useful information that might help to develop and adapt effective policies for TB control in Romania.

Author Biographies

Pacifique Ndishimye, a: National Institute of Hygiene, Rabat - Morocco b: Faculty of Sciences, Mohammed V University, Rabat - Morocco c: “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj Napoca - Romania

Faculty of Sciences, Mohammed V University, Rabat - Morocco

Bianca Domokos, UMF CLUJ NAPOCA “Leo Daniello” Pneumology Hospital, Cluj Napoca - Romania

Pulmonology Department

Jonathan Stillo, The City University of New York Graduate Center, New York - USA

Anthropology Department

Fouad Seghrouchni, National Institute of Hygiene, Rabat - Morocco

National Institute of Hygiene, Rabat - Morocco

Oulaya Mrabet, Ibn Tofail University, Kénitra - Morocco

Ibn Tofail University, Kénitra - Morocco

Daniela Homorodean, "Leon Daniello” Pneumology Hospital, Cluj Napoca

Pulmonology

Carmen Monica Pop, Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj Napoca - Romania

Pulmonology

Abderrahim Sadak, Faculty of Sciences, Mohammed V University, Rabat - Morocco

Faculty of Sciences, Mohammed V University, Rabat - Morocco

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Published

2017-01-30

How to Cite

1.
Ndishimye P, Domokos B, Stillo J, Seghrouchni F, Mrabet O, Homorodean D, Pop CM, Sadak A. A case control study of risk factors associated with pulmonary tuberculosis in Romania: Experience at a clinical hospital of pneumology. Med Pharm Rep [Internet]. 2017 Jan. 30 [cited 2025 Oct. 5];90(1):54-9. Available from: https://medpharmareports.com/index.php/mpr/article/view/652

Issue

Vol. 90 No. 1 (2017)

Section

Original Research

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