Primary non-Hodgkin diffuse large B-cell lymphoma of the lacrimal sac: a rare case of aggressive tumor and literature review

Authors

  • Maria Gabriella Malzone Pathological Anatomy Service, Maria Rosaria Clinic, Pompeii, Naples, Italy
  • Marzio Di Meglio Pathological Anatomy Service, Maria Rosaria Clinic, Pompeii, Naples, Italy
  • Dario Furgiuele Pathological Anatomy Service, Maria Rosaria Clinic, Pompeii, Naples, Italy
  • Nicola Galantuomo Ophthalmology center LASERVISTA, via Santa Chiara, Caserta, Italy
  • Sabrina Alfano Pathological Anatomy Service, Maria Rosaria Clinic, Pompeii, Naples, Italy
  • Gennaro Mossetti Pathological Anatomy Service, Maria Rosaria Clinic, Pompeii, Naples, Italy

DOI:

https://doi.org/10.15386/mpr-1926

Keywords:

non-Hodgkin diffuse large B-cell lymphoma, lacrimal sac, epiphora, polychemotherapy

Abstract

Primary malignant lymphomas of the lacrimal sac are rare neoplasms. They are mainly B-cell lymphoma with nonspecific and atypical symptoms, which can lead to misdiagnosis and a delay in the appropriate cure. Early diagnosis made by biopsy and the right choice of treatments can increase the chance of survival. We report a case of a non-Hodgkin diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac, involving also the drainage system, in a 77-year-old female. She presented with an epiphora, swelling and a heavy visual impairment at the left eye successfully treated with cycles of polychemotherapy and radiotherapy.

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Published

2021-06-30

How to Cite

1.
Malzone MG, Di Meglio M, Furgiuele D, Galantuomo N, Alfano S, Mossetti G. Primary non-Hodgkin diffuse large B-cell lymphoma of the lacrimal sac: a rare case of aggressive tumor and literature review. Med Pharm Rep [Internet]. 2021 Jun. 30 [cited 2025 Jul. 14];94(3):377-81. Available from: https://medpharmareports.com/index.php/mpr/article/view/1926

Issue

Vol. 94 No. 3 (2021)

Section

Case Report

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