Mckittrick-Wheelock syndrome: A rare case report of acute renal failure

Authors

DOI:

https://doi.org/10.15386/cjmed-536

Keywords:

tubular-villous adenoma, hydro-electrolytic disturbances, renal failure

Abstract

Giant tubular-villous adenoma of the rectum can determine secretory diarrhea, associated with a depleting syndrome of prerenal acute renal failure, hyponatremia, hypokalemia and hypoproteinemia. These symptoms are known as the McKittrick-Wheelock syndrome, and there are about 50 cases reported in literature. We present the case of a 59-year-old woman presented to our emergency department with abdominal pain, prerenal azotemia, and electrolyte disturbances with a background of chronic diarrhea, caused by a giant rectal tumor. Conservative therapy initially improved and normalized renal function, and made surgical resection of the tumor possible.

Author Biographies

Emil Ioan Mois, University of Medicine and Pharmacy “Iuliu Hatieganu” - E. Isac street 13, 400162, Cluj-Napoca, Romania Regional Institute of Gastroenterology and Hepatology “Prof. O. Fodor”, Surgery Department, Croitorilor street 19-21, 400023, Cluj-Napoca, Romania

Surgery Department

Florin Graur, University of Medicine and Pharmacy “Iuliu Hatieganu” - E. Isac street 13, 400162, Cluj-Napoca, Romania Regional Institute of Gastroenterology and Hepatology “Prof. O. Fodor”, Surgery Department, Croitorilor street 19-21, 400023, Cluj-Napoca, Romania

Surgery Department

Roxana Sechel, Regional Institute of Gastroenterology and Hepatology “Prof. O. Fodor”, Surgery Department, Croitorilor street 19-21, 400023, Cluj-Napoca, Romania

Department of Pathology

Nadim Al-Hajjar, University of Medicine and Pharmacy “Iuliu Hatieganu” - E. Isac street 13, 400162, Cluj-Napoca, Romania Regional Institute of Gastroenterology and Hepatology “Prof. O. Fodor”, Surgery Department, Croitorilor street 19-21, 400023, Cluj-Napoca, Romania

Surgery Department

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Published

2016-04-21

How to Cite

1.
Mois EI, Graur F, Sechel R, Al-Hajjar N. Mckittrick-Wheelock syndrome: A rare case report of acute renal failure. Med Pharm Rep [Internet]. 2016 Apr. 21 [cited 2025 Oct. 6];89(2):301-3. Available from: https://medpharmareports.com/index.php/mpr/article/view/536

Issue

Vol. 89 No. 2 (2016)

Section

Case Report

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